BIORCHESTRA is an innovative biotech company focusing on research and development of ribonucleic acid (RNA) based therapeutics. Our goal is to change the therapeutic paradigm from treating the symptoms to modifying the progression of the disease process. As we are making steady progress towards selecting our lead clinical candidate, we are therefore looking for an exceptional candidate Clinical Pharmacology to collaborate closely with our early development teams and lead our early human studies.
Based in Daejeon, South Korea, and Cambridge, MA, BIORCHESTRA has identified a novel pathway of neuroinflammation that is involved in neurodegenerative diseases and has developed proprietary drugs and targeting formulations that allow delivery to the brain through systemic administration.
Head of Clinical Pharmacology (and Biostatistics)
This position will be based in Cambridge, MA, and will report to the Chief Medical Officer of the company.
The successful candidate will have senior-level experience in Human Pharmacology and Drug Development and will have experience in the translational phase of development pharmacology from nonclinical to clinical.
The candidate will have advanced skills in the use of innovative analytical methods to integrate knowledge of pharmacokinetics (PK), biopharmaceutics, pharmacodynamics (PD), patient characteristics and disease states to optimize doses, dosage regimens and study designs, and will work closely with the project team to create clinical development plans that include assessments of a drug’s efficacy, safety, and to optimize clinical utility and commercial viability.
The candidate will have experience in working in team, leading teams, and achieving success through external collaborations and outsourcing.